Neonatal Bilirubin — AAP 2022

Phototherapy & exchange-transfusion thresholds for infants ≥35 weeks, by gestational age, hours of age and neurotoxicity risk.

Gestational age at birth

Age at measurement (hours) 0–336 h (to 14 days)

Total serum bilirubin (TSB)

Albumin (optional, for B/A ratio)

Neurotoxicity risk factors (other than gestational age)

Isoimmune hemolytic disease G6PD deficiency Asphyxia Significant lethargy Temperature instability Sepsis Acidosis Albumin < 3.0 g/dL

Optional — date/time helper & rate of rise

Date & time of birth

Date & time of measurement

Previous TSB (mg/dL)

…at age (hours)

Phototherapy at

–

mg/dL

Exchange at

–

mg/dL

Patient TSB

–

mg/dL

Thresholds per the 2022 AAP clinical practice guideline (Kemper et al., Pediatrics 2022). Conversion: µmol/L = mg/dL × 17.1.

Decision support only — confirm against the official AAP 2022 nomograms and your institution’s protocol, and interpret with the full clinical picture (trend, exam, feeding). Not a substitute for clinical judgment.